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In tries to explain these phenomena, scientists and scientists for the College of Science of Chulalongkorn University have attributed these seemingly preternatural phenomena to standing waves in h2o, and posit which the existence with the Phaya Nāga is analogous to perception in Loch Ness Monster in Scotland or Ogopogo in copyright, and further more manage which the serpent-like tracks from the Phaya Nāga are certainly maybe cast by human beings.[sixty nine]
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b may be the dissociation continual from the group that needs to be protonated for full exercise. The pH profiles which showed the deprotonation of two acid ic groups as well as the protonation of 1 simple group are expected for maximum action had been in shape to equation 5 where K
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As a result of powerful relation with all the things water, the Nāga in Thai belief also plays a role in rain Manage. The strategy of Nak hai nam (Thai: นาคให้น้ำ; lit. Nāga granting water) is utilized for annual rainfall prediction.
It could be argued, nonetheless, that if NagA ended up limited by product or service release from your Lively site, then the dissociation of trifluoroacetate may very well be inherently more rapidly than the release of acetate. This certain situation was dealt with because of the utilization of alterations in solvent viscosity to systematically alter the rate constants with the association and dissociation of solutions and substrates with NagA (19, twenty).
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using a battery of substrate analogs and Energetic web page mutants utilizing a host of steel-substituted forms of the enzyme. We conclude from these studies that NagA from E. coli